Strain Differences Associated with Refractory Lyme Arthritis

One strain of Borrelia burgdorferi appears to be more frequent in patients with antibiotic-refractory Lyme arthritis, researchers say.

“Our results add to the emerging literature concerning the differential pathogenicity of strains of B. burgdorferi,” the researchers said.

The tick-borne spirochete causes Lyme disease, which often begins with erythema migrans, an expanding skin lesion. The spirochetes frequently disseminate within a week to the nervous system, heart, and joints, often promoting arthritis.

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Childhood Arthritis: Common but Preventable Consequence of Lyme Disease

When left untreated, children infected with Lyme disease can experience many severe complications as a result including arthritis, problems with the heart or central nervous system.

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